In short
Yes, for some people. Two medicines are now approved in several countries for MASH with moderate or advanced scarring. They work alongside lifestyle change, not instead of it.
One is a daily tablet that helps the liver burn fat. The other is a weekly injection from the GLP-1 family that also lowers weight.
They are for adults with MASH and stage F2–F3 fibrosis, without cirrhosis. People with only simple fatty liver usually do not need them.
Medicines for diabetes and weight, such as GLP-1 injections, can also help the liver. Your doctor will decide what fits you, and what is available in your country.
Related questions
- Are statins (cholesterol pills) safe for my liver?
- Does weight-loss surgery help the liver?
- Do herbs, "detox" or supplements help?
Sources
- EASL–EASD–EASO Clinical Practice Guidelines on the management of MASLD. J Hepatol 2024;81:492–542. Link
- Madrigal Pharmaceuticals. European Commission approval of Rezdiffra, 19 August 2025. Link
- British Liver Trust. Two MASH treatments receive MHRA approval, 2026. Link
- Younossi ZM, et al. Updated global consensus recommendations for risk stratification, treatment initiation, and response monitoring in MASLD. Clin Gastroenterol Hepatol 2026;24(9):2333–47. Link
Last updated 2026-10-03. Based on international and Saudi guidelines. Education only: it does not replace your doctor. Read the disclaimer.